Dare to think about doing less
So, more is not always better – and this message remains important. Today, in women with metastatic (widespread) breast cancer, there is considerable enthusiasm for treatments such as Herceptin. Yet, at best, Herceptin offers these patients a small chance of a longer life – measured sometimes only in days or weeks – at the expense of serious side effects, or sometimes even death from the treatment itself. [12,13]
The classical radical mastectomy
The radical mastectomy, devised in the late 19th century by William Halsted, was the most commonly performed operation for breast cancer until the third quarter of the 20th century.
Meanwhile, the need for routine surgery to remove lymph nodes in the armpit, which risks unpleasant complications affecting the arm such as lymphoedema, is being increasingly challenged, since its addition to other treatments does not seem to improve survival. 
More: References (Section 3)
- More intensive treatment is not necessarily beneficial, and can sometimes do more harm than good.
Next Chapter: Earlier is not necessarily better
GET-IT Jargon Buster
GET-IT provides plain language definitions of health research terms