2-15 Fair comparisons with few people or outcome events can be misleading

When there are only few outcome events, differences in outcome frequencies between the treatment comparison groups may easily have occurred by chance and may mistakenly be attributed to differences between the treatments.

Be cautious about relying on the results of treatment comparisons with few outcome events. The results of such comparisons could be misleading.

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Know Your Chances

This book has been shown in two randomized trials to improve people's understanding of risk in the context of health care choices.

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Therapy

A University of Massachusetts Medical School text discussing the strengths and limitations of different measures of the effects of treatment

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What are the results?

A Duke Univ. tutorial explaining how to address the questions: How large was the treatment effect? What was the absolute risk reduction?

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Mega-trials

In this 5 min audio resource, Neeraj Bhala discusses systematic reviews and the impact of mega-trials.

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Pre-eclampsia in pregnant women

Another outstanding example of good research concerns pregnant women. Worldwide, about 600,000 women die each year of pregnancy-related complications. Most […]

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