2-14 Fair comparisons with few people or outcome events can be misleading

When there are only few outcome events, differences in outcome frequencies between the treatment comparison groups may easily have occurred by chance and may mistakenly be attributed to differences between the treatments.

Be cautious about relying on the results of treatment comparisons with few outcome events. The results of such comparisons could be misleading.

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Know Your Chances

This book has been shown in two randomized trials to improve peoples' understanding of risk in the context of health care choices.

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Mega-trials

In this 5 min audio resource, Neeraj Bhala discusses systematic reviews and the impact of mega-trials.

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